Triterpenoid α-amyrin stimulates proliferation of human keratinocytes but does not protect them against UVB damage.

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Triterpenoid α-amyrin stimulates proliferation of human keratinocytes but does not protect them against UVB damage.

Rhaponticum carthamoides plants ("maral root") are widely used in Siberian folk medicine. The present study reports for the first time the presence of pentacyclic terpenoid, α-amyrin, in methanol extract from leaves of this plant. α-Amyrin induced proliferation of human keratinocytes (HaCaT) by about 18% while other extract components were ineffective. A panel of biochemical and cell-based ass...

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ژورنال

عنوان ژورنال: Acta Biochimica Polonica

سال: 2012

ISSN: 1734-154X,0001-527X

DOI: 10.18388/abp.2012_2147